Effectiveness of aripiprazole v. Haloperidol in acute bipolar mania
نویسندگان
چکیده
منابع مشابه
comparison the effectiveness of aripiprazole and risperidone for the treatment of acute bipolar mania
background: second-generation antipsychotics, approved for the treatment of mania, are associated with adverse effects such as weight gain and metabolic disorders. aripiprazole, a recently introduced second-generation antipsychotic, are thought to account for its low propensity for weight gain, metabolic disturbances and sedation. the purpose of this study was to investigate the effect of rispe...
متن کاملComparison the effectiveness of aripiprazole and risperidone for the treatment of acute bipolar mania
BACKGROUND Second-generation antipsychotics, approved for the treatment of mania, are associated with adverse effects such as weight gain and metabolic disorders. Aripiprazole, a recently introduced second-generation antipsychotic, are thought to account for its low propensity for weight gain, metabolic disturbances and sedation. The purpose of this study was to investigate the effect of risper...
متن کاملAripiprazole monotherapy in acute mania: 12-week randomised placebo- and haloperidol-controlled study.
BACKGROUND Well-tolerated and effective therapies for bipolar mania are required. AIMS To evaluate the efficacy and tolerability of aripiprazole as acute and maintenance of effect therapy in patients with bipolar I disorder experiencing manic or mixed episodes. METHOD Patients were randomised to double-blind aripiprazole (15 or 30 mg/day; n=167), placebo (n=153) or haloperidol (5-15 mg/day,...
متن کاملWhen to start aripiprazole therapy in patients with bipolar mania
Aripiprazole is a third generation atypical antipsychotic with compelling evidence as a highly effective treatment option in the management of acute manic and mixed episodes of bipolar I disorders. It has a unique mode of action, acting as a partial agonist at dopamine D2 and D3, and serotonin 5-HT1A; and exhibiting antagonistic action at the 5-HT2A and H1 receptors. Overall, it has a favorable...
متن کاملQuetiapine for acute mania in bipolar disorder.
PURPOSE The efficacy and tolerability of quetiapine in the treatment of acute mania were reviewed. SUMMARY Five randomized, placebo-controlled trials involving quetiapine as monotherapy or adjunct therapy in combination with either divalproex or lithium in the treatment of bipolar mania in either adolescents or adults were identified and reviewed. The primary outcome measure used in the trial...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 2005
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.187.3.235